Project Details
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Redesign of allosteric regulation of enzyme for self-regulated dynamic control of metabolic fluxes in microbial amino acid production

Subject Area Biological Process Engineering
Pharmacy
Term from 2011 to 2016
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 203132763
 
Final Report Year 2017

Final Report Abstract

No abstract available

Publications

  • (2017) Analysis of intracellular metabolites of Corynebacterium glutamicum at high cell density with automated sampling and filtration and assessment of engineered enzymes for effective l-lysine production. Engineering in life sciences 17 (5) 512–522
    Da Luz, Julian A.; Hans, Enrico; Frank, Doinita; Zeng, An-Ping
    (See online at https://doi.org/10.1002/elsc.201600163)
  • (2015) Rational design of allosteric regulation of homoserine dehydrogenase by a non-natural inhibitor L-lysine. ACS Synthetic Biology. 4(2):126-131
    Z. Chen, S. Rappert and A.-P. Zeng
    (See online at https://doi.org/10.1021/sb400133g)
  • (2016) Protein engineering approaches to chemical biotechnology. Current Opinion in Biotechnology. 42: 198–205
    Z. Chen and A.-P. Zeng
    (See online at https://doi.org/10.1016/j.copbio.2016.07.007)
  • (2018) Engineering Biomolecular Switches for Dynamic Metabolic Control. In: A.-P. Zeng, H. Zhao (eds.) Synthetic Biology and Metabolic Engineering. Adv. Biochem. Eng. /Biotechnol., vol. 162. S. 45–76
    C.-W. Ma, L.–B. Zhou and A.-P. Zeng
    (See online at https://doi.org/10.1007/10_2016_9)
 
 

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