Spatial modeling of gradient sensing exemplified for the yeast pheromone response
(D08)
Subject Area
Bioinformatics and Theoretical Biology
Term
from 2011 to 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 25065445
Yeast cells mate using pheromone secretion and sensing and directed protrusion formation. Employing a combination of fluorescence and atomic force microscopy with spatiotemporal mathematical modeling, we will investigate the role of functional modules in three types of processes: i) pattern formation of pheromones, ii) implementation of stable spatial cell response, and iii) induction and mechanics of cell shape change. On top, we study principles of mutual information exchange among the mating cells.
DFG Programme
Collaborative Research Centres
