Value-coding of dopamine neuron populations in olfactory processing (A04)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells ; Cognitive, Systems and Behavioural Neurobiology
• Term: from 2010 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 118803580

In animals, value based decision-making depends on prior experience and current internal state. Which neurons take part in this type of decision-making, their coding principles, and neural network properties are not well understood. The aim of this project is to unravel the modulatory role of dopaminergic neurons in internal state and experience-dependent olfactory processing in two different model systems (fly mushroom body, mouse olfactory bulb). To this end, we are using in vivo volumetric imaging and automated unbiased image analysis in combination with state-of-art genetics and behavioral analysis.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 870: Assembly and Function of Neuronal Circuits in Sensory Processing
• Applicant Institution: Ludwig-Maximilians-Universität München
• Project Head: Professorin Dr. Ilona Grunwald Kadow