Professor Dr. Peter Hegemann

Address Humboldt-Universität zu Berlin
Institut für Biologie
Arbeitsgruppe Experimentelle Biophysik
Invalidenstraße 42
10115 Berlin

Projects

As Applicant
- Current projects
  - Functional in vivo Studies of Algal Sensory Photoreceptors (Research Grants)
- Completed projects
  - Molecular mechanisms of gene silencing and positional effects in Green Algae (Research Units)
  - Biochemical and spectroscopic characterization of blue light receptors with LOV and BLUF-domain-type chromophores from microalgae and purple bacteria (Research Units)
  - Zentralprojekt (Research Units)
  - Nuclear gene targeting in Chlamydomonas reinhardtii (Research Units)
  - Der Photochromismus des Channelrhodopsin-1 aus Volvox carteri (VCHR) (Research Grants)
  - Central Project (Research Units)
  - The Channelrhodopsin mechanism (Research Grants)
  - Investigation of BLUF photochemistry by isotopic labeling of flavin cofactor and amino acid side chains (Research Grants)
  - Ultrafast dynamics of biomolecules studied by vibrational spectroscopy on selectively isotope labeled proteins (Research Grants)
  - Functional characterization of novel rhodopsins of Chlamydomonas and other algae (Research Units)
  - Central Project (Research Units)
  - Optogenetic dissection of the developing prefrontal-hippocampal circuitry that gates mnemonic and executive maturation (Priority Programmes)
  - Channelrhodopsin colour tuning (Research Units)
  - Characterization of biomodal light-switchable rhodopsins and tailoring for optogentic application (Research Units)
  - Central Coordination Project (Research Units)
  - Development and Application of New Optogenetic Tools Targeted to Intracellular Compartments (Priority Programmes)
  - Cognitive performance as result of coordinated neuronal activity within developing prefrontal-hippocampal circuits (Priority Programmes)
  - Engineering of Chrimson for Subcellular Optogenetic application (Priority Programmes)
  - Development and application of RoCK, a novel Rhodopsin Cyclase/ K+ channel-based optogenetic tool for silencing of excitable cells (Priority Programmes)
  - Shrimp Rhodopsins as new far-red absorbing optogenetic tools (Priority Programmes)
  - Probing functional connectivity in vivo via holographic and molecular targeting (Research Grants)
As Leader
- Completed projects
  - FTIR Spektrometer mit Laseranregungssystem (Major Research Instrumentation)
As Spokesperson
- Completed projects
  - FOR 526: Blue-light Sensitive Photoreceptors (Research Units)
  - FOR 1279: Protein-based Photoswitches as Optogenetic Tools (Research Units)
As Participating Researcher
- Current projects
  - EXC 2008: UniSysCat (Clusters of Excellence (ExStra))
  - EXC 2049: NeuroCure (Clusters of Excellence (ExStra))
- Completed projects
  - EXC 314: Unifying Concepts in Catalysis (Clusters of Excellence)
As Project Head
- Current projects
  - Development of molecular tools for manipulating and studying memory engrams (Collaborative Research Centres)
- Completed projects
  - Sensorische Rhodopsine einzelliger Algen (Collaborative Research Centres)
  - Rhodopsinregulierte ionale Signalprozesse in Chlamydomonas und Volvox (Collaborative Research Centres)
  - Expression and spectroscopic characterization of channelrhodopsins and enzymerhodopsins from Chlamydomonas reinhardtii (Collaborative Research Centres)
  - Optical control of calcium switches that orchestrate fast signaling in the brain. (CRC/Transregios)
  - Proton exchange processes in phytochromes and retinal proteins investigated by MAS NMR (Collaborative Research Centres)
  - Gating and ion transport dynamics in channelrhodopsins and light-driven pumps (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Biochemical and spectroscopic characterization of three blue light receptors with LOV and BLUF-domain-type chromophores (Research Units)
  - A modular dual 2-photon microscope for multimodal optogenetics, synapse biophysics and beyond (Major Instrumentation Initiatives)
  - Lattice Light Sheet Microscope (LLSM) (Major Instrumentation Initiatives)
As Co-Investigator
- Completed projects
  - Optogenetic dissection of cyclic nucleotide signaling in a model parasite Toxoplasma gondii (Research Grants)

As Prizewinner
- Gottfried Wilhelm Leibniz-Programm 2013