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Project Details

Person

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Professorin Dr. Michaela Gack

Address Cleveland Clinic
Lerner Research Institute
9500 Euclid Avenue
Cleveland OH 44195
USA

Projects

As Host
- Completed projects
  - Regulation of RIG-I-mediated anti-viral innate immunity by post-translational modifications (Research Fellowships)
  - The proposed project aims at deciphering the molecular mechanism of the inhibition of the TRIM25/RIG-I-mediated interferon response by the influenza A virus NS1 protein with the main focus on the characterization of the TRIM25-NS1 interaction and NS1 mutant viruses, incapable of binding TRIM25. (Research Fellowships)
  - Identification of cellular restriction factors against herpesviral infection (Research Fellowships)
  - TRIM proteins in autophagy-mediated antiviral defense (Research Fellowships)

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