Professor Dr. Marc Freichel

Address Ruprecht-Karls-Universität Heidelberg
Pharmakologisches Institut
Im Neuenheimer Feld 366
69120 Heidelberg

Projects

As Applicant
- Current projects
  - Development of new compounds to define the potential of TRPM4 inhibition for prevention and suppression of Ca2+ dependent cardiac arrhythmias. (Research Grants)
  - Neuronal NAADP signalling during neuroinflammation (Research Units)
- Completed projects
  - Rolle von TRP-Kanälen beim kardialen Remodelling (Clinical Research Units)
  - The role of TRPC1 C4 C5 C6 and related proteins for Ca2+ signaling in mast cells (Priority Programmes)
  - Neuronal intracellular Ca2+ stores in inflammatory neurodegeneration. (Research Units)
As Participating Researcher
- Completed projects
  - GRK 1874: Diabetic Microvascular Complications (DIAMICOM) (International Research Training Groups)
As Project Head
- Current projects
  - Adenine nucleotide signaling in Ca2+-dependent mast cell activation: role of endolysosomal and plasmalemmal channels (Collaborative Research Centres)
  - Functional and molecular specificity of OCaR-control of intracellular Ca2+ release (CRC/Transregios)
  - Unraveling molecular circuits leading to catecholamine-driven ventricular arrhythmias (Collaborative Research Centres)
  - Integrated Research Training Group for CardioScience (Collaborative Research Centres)
- Completed projects
  - Deletion and analysis of the function of calcium channels in mice (Collaborative Research Centres)
  - The membrane proteins TMEM1, 2 and 4 (Collaborative Research Centres)
  - TRPC cation channels in hypoglycemia-associated autonomic nervous system failure in diabetes models (Collaborative Research Centres)
  - Platform for CRISPR/Cas technology and AAV atherosclerosis model (Collaborative Research Centres)