Professor Dr. Christian Buske

Address Universitätsklinikum Ulm
Institut für Experimentelle Tumorforschung
Albert-Einstein-Allee 11
89081 Ulm

Projects

As Applicant
- Current projects
  - Deciphering Critical Changes in the Methylome of Hematopoietic Stem Cells in Age-related Clonal Hematopoiesis and Myeloid Leukemogenesis (Research Units)
- Completed projects
  - Pathogenetische Bedeutung des humanen leukämie-spezifischen Fusionsgens TEL-CDX2 und des Homeoboxgens CDX2 in der t(12;13)(p13;q12) positiven akuten myeloischen Leukämie (Research Grants)
  - Bedeutung des Lymphoid Enhancer Factor 1 (LEF1) in der normalen und malignen Hämatopoese (Research Grants)
  - Dissecting the role of PIWIL4 as a novel epigenetic factor in acute myeloid leukemia (Priority Programmes)
As Leader
- Completed projects
  - Genomsequenziergerät (Major Research Instrumentation)
  - Zellsortierer (Major Research Instrumentation)
  - Durchflusszytometer (Major Research Instrumentation)
As Participating Researcher
- Completed projects
  - GSC 270: International Graduate School in Molecular Medicine Ulm (Graduate Schools)
  - GRK 1789: Cellular and Molecular Mechanisms in Aging (CEMMA) (Research Training Groups)
As Project Head
- Current projects
  - Characterization of endogenous peptides targeting leukemic stem cells in acute myeloid leukemia (Collaborative Research Centres)
- Completed projects
  - Mechanisms of ParaHox gene induced leukemogenesis (Collaborative Research Centres)
  - Hyperpolarized peptide-coated nanodiamonds for magnetic resonance imaging (Collaborative Research Centres)
  - Dissecting of the function of the “Lymphoid enhancer-binding factor 1” (Lef1) in acute myeloid leukemia (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Mechanismen der Transformation hämatopoetischer Zellen durch AML-spezifische Mutationen der Rezeptortyrosinkinase FLT3 in vitro und in vivo (Research Grants)
  - Functional evaluation of DNA methylation-controlled leukemia stem cell genes (Priority Programmes)