Project Details

Professor Dr. Dirk Isbrandt

Address Universitätsklinikum Köln
Institut für Molekulare und Verhaltensneurowissenschaften
Kerpener Straße 62
50937 Köln

ORCID-ID 0000-0002-4720-1016

Projects

As Applicant
- Current projects
  - Centralized data management and analysis facilities (Research Units)
  - Molecular and network mechanisms-derived targeted interventions in neonatal genetic epilepsies (Research Units)
  - Transcriptomic and epigenetic profiles of basal ganglia-cortex networks in developmental epileptic encephalopathies (Research Grants)
- Completed projects
  - Analyse von hippocampalen Oszillationen in KCNQ/M-Kanal-defizienten transgenen Mäusen (Research Grants)
  - Untersuchungen zur Pathophysiologie von Epilepsien des Neugeborenen- und Säuglingsalters in transgenen Mausmodellen (Research Grants)
  - Analysis of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function in adult heart using conditional transgenic mouse models (Research Units)
  - Experimentelle Neuropädiatrie (Heisenberg Professorships)
  - High-resolution characterization of functional connectivity and behavior in healthy and transgenic mice from the neonatal period through adulthood (Priority Programmes)
  - Consequences of HCN/h pacemarker channel deficency for cortico-basal ganglia circuit function (Clinical Research Units)
  - Single-cell transcriptome sequencing to investigate mechanisms of epileptogenesis in genetic mouse models and human brain biopsy tissue (Research Grants)
As Project Head
- Current projects
  - Developmental mechanisms affecting motor skills and motor control (Collaborative Research Centres)
  - Dentate gyrus activity patterns and their intra-hippocampal coordination in behavior and disease (Collaborative Research Centres)
- Completed projects
  - Analyse von Phänotyp und Pathophysiologie der Guanidinoacetat N-Methyltransferase Defizienz des Menschen mit Hilfe eines Mausmodells (Collaborative Research Centres)
  - Network mechanisms underlying information transfer in the entorhinal cortex-hippocampus circuitry during learning and memory (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Arrhythmogenesis associated with mutations in KCNH2 (HERG) (Research Grants)
  - Physiologie und Pathophysiologie Arginin-Glyzin-Amidinotransferase (AGAT)-defizienter Mäuse (Research Grants)

Servicenavigation

Hauptnavigation

Professor Dr. Dirk Isbrandt

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Dirk Isbrandt

Additional Information

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