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Professor Dr. Thomas Klein

Address Heinrich-Heine-Universität Düsseldorf
Institut für Genetik
Universitätsstraße 1
40225 Düsseldorf

Projects

As Applicant
- Current projects
  - Elucidating divergent regulation of mammalian Notch ligands by Mindbomb1 using humanized Drosophila (Research Grants)
  - Characterisation of the co-adapter function of the E3 ligase Neuralized (Neur) during DSL-ligand induced Notch signalling (Research Grants)
- Completed projects
  - Charakterisierung eines Prozesses zur Festsetzung von Entscheidungsschwellenwerten (Research Grants)
  - Unravelling the molecular network of Lethal (2) giant discs (Lgd) in Drosophila melanogaster. (Research Grants)
  - The role of lysines of the intracellular domain of Notch during regulation of the Notch pathway (Research Grants)
  - The role of cis-inhibition during selection of the neural precursor cell (Research Grants)
  - Determining the function of Lgd/CC2D1 in mouse (Research Grants)
  - The function of the ESCRT machinery in the maintenance of the septate junction of Epithelia in Drosophila (Research Grants)
  - Binding and regulation of the activity of the DSL ligand Serrate by E3 ligases (Research Grants)
As Leader
- Completed projects
  - Spinning Disc Konfokalmikroskop (Major Research Instrumentation)
As Project Head
- Current projects
  - Understanding the function of Lethal (2) giant discs (Lgd) and ESCRT-III (Collaborative Research Centres)
- Completed projects
  - Regulation der Aktivität des Notch-Signalwegs und Funktion des Gens defective proventriculus (dve) während der Musterbildung in den Imaginalscheiben von Drosophila melanogaster (Collaborative Research Centres)
  - The function of the tumour suppressor gene lethal (2) giant discs (lgd) during the development of Drosophila and Mouse (Collaborative Research Centres)

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