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Professor Dr. Roland Beckmann

Address Ludwig-Maximilians-Universität München
Gene Center Munich
Feodor-Lynen-Straße 25
81377 München

Projects

As Applicant
- Current projects
  - Structural and functional analysis of the ribosomal quality control trigger complex RQT (Research Grants)
  - Stop codon readthrough lessons from the tRNA anti-codon stem. (Research Grants)
  - Molecular mechanism of recognizing individual stalled ribosomes by the E3 ligases Mag2 and Fap1 (Research Grants)
- Completed projects
  - Aufklärung der Struktur des Oxa1-Ribosomen-Komplexes mittels hochauflösender Elektronenmikroskopie (Research Grants)
  - Analysis of the structure of the Oxa1-ribosome-complex by high-resolution cyro-electron microscopy (Research Units)
  - Functional characterization of the ribosomal tunnel exit ligand ERj1 (Research Units)
  - Structural basis of canonical and non-canonical translation termination and recycling by eRF1/eRF3 and ABCE1 in yeast and humans (Research Units)
  - Structural and functional characterization of a SKI sub complex in Saccharomyces cerevisiae (Research Grants)
  - Characterization of ribosomal stalling sequences and their recognition by the RQT quality control factors (Research Grants)
As Leader
- Completed projects
  - Direct Electron Detector for cryo-electron microscopy (Major Research Instrumentation)
  - 300 keV FEG Electron Cryo Microscope for Single Particle Analyses and Tomography (Major Research Instrumentation)
  - Electron detector and energy filter for an high-resolution cryo-electron microscope (Major Research Instrumentation)
As Spokesperson
- Completed projects
  - SFB 594: Molecular Machines in Protein Folding and Protein Transport (Collaborative Research Centres)
  - SFB 646: Networks in Genome Expression and Maintenance (Collaborative Research Centres)
As Participating Researcher
- Completed projects
  - GRK 1721: Integrated Analysis of Macromolecular Complexes and Hybrid Methods in Genome Biology (Research Training Groups)
  - EXC 114: Munich Center for Integrated Protein Science (CIPSM) (Clusters of Excellence)
  - GSC 1006: Graduate School of Quantitative Biosciences Munich (QBM) (Graduate Schools)
As Project Head
- Completed projects
  - Struktur des proteinleitenden Kanals bei der Insertion eines polytopischen Membranproteins, des Opsins (Collaborative Research Centres)
  - Visualization of the ribosometranslocon complex: nascent transmembrane domains in the ribosomal tunnnel and the active translocon in the membrane (Collaborative Research Centres)
  - The functional architecture of the ribosome-NAC complex and its role in protein targeting (Collaborative Research Centres)
  - Cryo-EM analysis of the ISWI chromatin remodeller ACF (CRC/Transregios)
  - Structural basis of eukaryotic non-stop mediated mRNA decay and mammalian translation initiation (Collaborative Research Centres)
  - Central tasks of the Collaborative Research Centre SFB 646 (Collaborative Research Centres)
  - Co-translational membrane targeting by SRP and FlhF (CRC/Transregios)
As Cooperation Partner
- Completed projects
  - Formation and maturation of the eukaryotic 60S ribosomal subunit (Research Grants)

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