Professor Dr. Klaus Pfeffer

Address Universitätsklinikum Düsseldorf
Institut für Medizinische Mikrobiologie und Krankenhaushygiene
Universitätsstraße 1
40225 Düsseldorf

Projects

As Applicant
- Completed projects
  - Funktionen des TNF-Rezeptors p55 und des Lymphotoxin Beta Rezeptors in vivo (Research Grants)
  - The role of the Lymphotoxin beta receptor in innate immunity (Priority Programmes)
  - The biological role of interferon y induced 65 kDa GBPs as effector molecules in host defense (Research Units)
  - Central tasks of the Research Unit 729 (Research Units)
  - Molecular functions of the murine guanylate binding protein (mGBP) 2 in the immune defense against Toxoplasma gondii (Research Grants)
As Spokesperson
- Completed projects
  - FOR 729: Anti-infective Effector Programmes: Signals and Mediators (Research Units)
As Participating Researcher
- Current projects
  - GRK 2158: Natural products and natural product analogs against therapy-resistant tumors and microorganisms: new lead structures and modes of action (Research Training Groups)
- Completed projects
  - GRK 1045: Modulation of Host Cell Functions to Treat Viral and Bacterial Infections (Research Training Groups)
  - GRK 1949: Immune Response in Infectious Diseases - Regulation between Innate and Adaptive Immunity (Research Training Groups)
As Project Head
- Completed projects
  - Aufklärung der Funktionen der Janus Kinase-2 (JAK2) (Collaborative Research Centres)
  - Generierung und Analyse eines Kinectin-defizienten Mausstammes (Collaborative Research Centres)
  - Analyse der Funktionen von Interferon y-induzierten Genen bei der angeborenen Infektionsabwehr (Collaborative Research Centres)
  - Herpesvirusinfektionen bei der Organtransplantation: Rolle des Cytomegalovirus bei der Pathogenese des chronischen Transplantatversagens (Collaborative Research Centres)
  - Generierung und Analyse von sodd-und tab2-defizienten Mausstämmen (Collaborative Research Centres)
  - The role of TNF recptor p55 (TNFRp55) for liver failure during acute sepsis and bacterial infections (Collaborative Research Centres)
  - Activation and differentiation of macrophages mediated by proinflammatory cytokines (Collaborative Research Centres)
  - Molecular Analysis of Lymphotoxin-ß-Receptor and Tumor Necrosis Factor Receptor p55 Mediated Hepatic Regeneration Processes (Collaborative Research Centres)
  - Dynamics and trafficking of mGBP protein complexes within membranous compartments (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Generation and characterization of a TRAP1 knockout mouse (Research Grants)

As Prizewinner
- Gottfried Wilhelm Leibniz-Programm 2004