Project Details

Professor Dr. Bernhard Brüne

Address Goethe-Universität Frankfurt am Main
Universitätsklinikum
Institut für Biochemie I: Pathobiochemie
Theodor-Stern-Kai 7
60596 Frankfurt am Main

Projects

As Applicant
- Current projects
  - Macrophages in sensing and executing ferroptosis (Priority Programmes)
- Completed projects
  - Wechselwirkung von Stickstoffmonoxid mit Cysteinproteasen (Research Grants)
  - Superoxid als Vermittler einer oxLDL-Wirkung auf Makrophagen (Research Grants)
  - Die Rolle von NO bei der Initiierung und Modulierung hypoxischer Antworten (Research Grants)
  - Desensitivierung von Makrophagen (Research Grants)
  - Einfluss bioaktiver Lipide aus apoptotischen Zellen auf den Makrophagenphänotyp (Research Units)
  - Role of mRNA stabilizing proteins during macrophage polarization and implications for tumor development (Research Grants)
  - PPARä and AMPK as regulators of lipid metabolism and polarization of macrophages (Research Grants)
  - Regulation of tumor-supporting monocyte infiltration and macrophage polarization by tumor cell HuR (Research Grants)
  - Tumorigenic cytokine networks during colon carcinogenesis depend on sphingosine-1-phosphate receptor signalling (Research Units)
  - S1P receptors shape immune cell plasticity in colorectal carcinoma (Research Units)
  - Hypoxia-controlled sterol and fatty acid synthesis with immune-modulatory consequences in myeloid cells (Research Grants)
As Spokesperson
- Completed projects
  - SFB 815: Redox-Regulation: Generating Systems and Functional Consequences (Collaborative Research Centres)
As Participating Researcher
- Current projects
  - GRK 2336: Resolution of inflammation – Mediators, signaling and therapeutic options (Research Training Groups)
- Completed projects
  - GRK 757: Roles of Eicosanoids in Biology and Medicine (International Research Training Groups)
  - GRK 1172: Research, Development and Safety of Biologicals (Research Training Groups)
As Project Head
- Current projects
  - Regulation and function of 15-lipoxygenase-2 (Collaborative Research Centres)
- Completed projects
  - Tubuloepitheliale und mesangiale Zellschädigung und Protektion durch Redoxsignale (Collaborative Research Centres)
  - Regulation und funktion des Proteasoms und der PPAR-Y-Expression bei der NO-vermittelten Apoptose und dem Schutz von Makrophagen (Collaborative Research Centres)
  - Consequences of chronic hypoxia and HIF-1/HIF-2 in regulating function and plastic-ity of macrophages and tumor cells (Collaborative Research Centres)
  - Administration (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Bedeutung von oxidativem Streß für die Endothelfunktionsstörung bei Patienten mit arterieller Hypertonie (Clinical Research Units)

Servicenavigation

Hauptnavigation

Professor Dr. Bernhard Brüne

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Bernhard Brüne

Additional Information

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