Humboldt-Universität zu Berlin
Institut für Biologie
Arbeitsgruppe Experimentelle Biophysik
Address
Invalidenstraße 42
10115 Berlin
Deutschland
GERiT
This institution in GERiT
10115 Berlin
Projects
Research Grants
Current projects
Functional in vivo Studies of Algal Sensory Photoreceptors
(Applicant
Hegemann, Peter
)
Neorhodopsins, Near-infrared sensing Rhodopsin-cyclases
(Applicants
Bartl, Franz
;
Broser, Matthias
)
Physical constraints to tune B-cell activation and differentiation
(Applicant
Klotzsch, Enrico
)
Completed projects
Der Photochromismus des Channelrhodopsin-1 aus Volvox carteri (VCHR)
(Applicants
Elstner, Marcus
;
Hegemann, Peter
)
Investigation of BLUF photochemistry by isotopic labeling of flavin cofactor and amino acid side chains
(Applicant
Hegemann, Peter
)
Optogenetic dissection of cyclic nucleotide signaling in a model parasite Toxoplasma gondii
(Applicant
Gupta, Nishith
)
Probing functional connectivity in vivo via holographic and molecular targeting
(Applicant
Hegemann, Peter
)
The Channelrhodopsin mechanism
(Applicant
Hegemann, Peter
)
Ultrafast dynamics of biomolecules studied by vibrational spectroscopy on selectively isotope labeled proteins
(Applicant
Hegemann, Peter
)
Research Units
Completed projects
Biochemical and spectroscopic characterization of blue light receptors with LOV and BLUF-domain-type chromophores from microalgae and purple bacteria
(Applicants
Hegemann, Peter
;
Schlichting, Ilme
)
Biochemical and spectroscopic characterization of three blue light receptors with LOV and BLUF-domain-type chromophores
(Applicant
Schlichting, Ilme
)
Central Coordination Project
(Applicant
Hegemann, Peter
)
Central Project
(Applicants
Hegemann, Peter
;
Mittag, Maria
)
Central Project
(Applicants
Hegemann, Peter
;
Mittag, Maria
;
Weber, Andreas P.M.
)
Channelrhodopsin colour tuning
(Applicants
Elstner, Marcus
;
Hegemann, Peter
)
Characterization of biomodal light-switchable rhodopsins and tailoring for optogentic application
(Applicant
Hegemann, Peter
)
FOR 526: Blue-light Sensitive Photoreceptors
(Spokesperson
Hegemann, Peter
)
FOR 1279: Protein-based Photoswitches as Optogenetic Tools
(Spokesperson
Hegemann, Peter
)
Functional characterization of novel rhodopsins of Chlamydomonas and other algae
(Applicant
Hegemann, Peter
)
Molecular mechanisms of gene silencing and positional effects in Green Algae
(Applicant
Hegemann, Peter
)
Nuclear gene targeting in Chlamydomonas reinhardtii
(Applicant
Hegemann, Peter
)
Zentralprojekt
(Applicant
Hegemann, Peter
)
Collaborative Research Centres
Current projects
Development of molecular tools for manipulating and studying memory engrams
(Project Heads
Hegemann, Peter
;
Rosenmund, Christian
;
Rost, Benjamin
;
Schmitz, Dietmar
;
Vierock, Johannes
)
Completed projects
Expression and spectroscopic characterization of channelrhodopsins and enzymerhodopsins from Chlamydomonas reinhardtii
(Project Head
Hegemann, Peter
)
Gating and ion transport dynamics in channelrhodopsins and light-driven pumps
(Project Heads
Budisa, Nediljko
;
Hegemann, Peter
)
Proton exchange processes in phytochromes and retinal proteins investigated by MAS NMR
(Project Heads
Hegemann, Peter
;
Oschkinat, Hartmut
)
Rhodopsinregulierte ionale Signalprozesse in Chlamydomonas und Volvox
(Project Head
Hegemann, Peter
)
Sensorische Rhodopsine einzelliger Algen
(Project Head
Hegemann, Peter
)
Major Research Instrumentation
Completed projects
FTIR Spektrometer mit Laseranregungssystem
Priority Programmes
Completed projects
Cognitive performance as result of coordinated neuronal activity within developing prefrontal-hippocampal circuits
(Applicants
Denker, Michael
;
Hanganu-Opatz, Ileana L.
;
Hegemann, Peter
;
Oertner, Thomas
)
Development and Application of New Optogenetic Tools Targeted to Intracellular Compartments
(Applicants
Hegemann, Peter
;
Rost, Benjamin
)
Development and application of RoCK, a novel Rhodopsin Cyclase/ K+ channel-based optogenetic tool for silencing of excitable cells
(Applicants
Baier, Herwig
;
Hegemann, Peter
;
Schneider-Warme, Franziska
;
Seifert, Ph.D., Reinhard
)
Engineering of Chrimson for Subcellular Optogenetic application
(Applicants
Elstner, Marcus
;
Hegemann, Peter
;
Rost, Benjamin
)
Optogenetic dissection of the developing prefrontal-hippocampal circuitry that gates mnemonic and executive maturation
(Applicants
Denker, Michael
;
Hanganu-Opatz, Ileana L.
;
Hegemann, Peter
;
Oertner, Thomas
)
Shrimp Rhodopsins as new far-red absorbing optogenetic tools
(Applicant
Hegemann, Peter
)
CRC/Transregios
Completed projects
Optical control of calcium switches that orchestrate fast signaling in the brain.
(Project Heads
Hegemann, Peter
;
Plested, Andrew
)
Major Instrumentation Initiatives
Completed projects
A modular dual 2-photon microscope for multimodal optogenetics, synapse biophysics and beyond
Lattice Light Sheet Microscope (LLSM)
Clusters of Excellence
Completed projects
EXC 314: Unifying Concepts in Catalysis
(Spokesperson
Drieß, Matthias
)
Clusters of Excellence (ExStra)
Current projects
EXC 2008: UniSysCat
(Spokespersons
Dobbek, Holger
;
Drieß, Matthias
;
Mroginski, Ph.D., Maria Andrea
;
Rappsilber, Juri
;
Thomas, Arne
)
EXC 2049: NeuroCure
(Spokespersons
Dirnagl, Ulrich
;
Schmitz, Dietmar
)
