Technische Universität München (TUM)
Fakultät für Medizin
Institut für Virologie
Address
Trogerstraße 30
81675 München
Deutschland
GERiT
This institution in GERiT
81675 München
Projects
Research Grants
Current projects
Junk-DNA” meets Developmental Biology: Investigating the influence of HERV-K(HML-2) on cortical neuronal differentiation
(Applicant
Vincendeau, Michelle
)
Spatio-temporal characterization of ERV expression and regulation in primate brain development
(Applicants
Klughammer, Ph.D., Johanna
;
Vincendeau, Michelle
)
Understanding the impact of endogenous viruses on host biology: a combined computational and experimental strategy
(Applicants
Frishman, Dmitrij
;
Vincendeau, Michelle
)
Completed projects
Calpain 15 activity in immune regulation
(Applicant
Pichlmair, Andreas
)
Characterisation and regulation of the alternative cap binding complex consisting of NCBP1 and -3
(Applicant
Pichlmair, Andreas
)
Characterization of a novel nucleotide based second messenger system regulating innate immune responses
(Applicant
Pichlmair, Andreas
)
Identification of host genetic variation predisposing to severe COVID-19 by genetics, transcriptomics and functional analyses
(Applicants
Gagneur, Julien
;
Pichlmair, Andreas
;
Schulte, Eva-Christina
)
Lebergerichteter Zytokin-Gentransfer: Einfluss auf die Hepatitis B Virus Replikation
(Applicant
Protzer, Ulrike
)
Rekombinante Hepatitis B Viren: Vektoren für eine lebergerichtete Gentherapie und molekulare Werkzeuge
(Applicant
Protzer, Ulrike
)
Speziesübergreifende Etablierung von Hepatitis B Virus Infektionen mittels adenoviraler Vektoren
(Applicant
Protzer, Ulrike
)
The interaction of Hepatitis B virus infection and Schistosomiasis in chronic pathogen-induced liver inflammation
(Applicants
Prazeres da Costa, Clarissa
;
Protzer, Ulrike
)
The role of cellular triphosphorylated-RNA interacting proteins in antiviral immunity
(Applicant
Pichlmair, Andreas
)
Viral Disease Mapping Initiative
(Applicant
Pichlmair, Andreas
)
WBP Position
Current projects
Determining molecular mechanisms linking SARS-CoV-2 infection to neuronal developmental defects and neurodegenerative disease
(Applicant
Strobelt, Romano
)
Mechanisms and regulation of nucleotide signalling pathways in humans
(Applicant
Bekere, Indra
)
Collaborative Research Centres
Completed projects
Cell autonomous defense in the control of hepatitis B virus infection
(Project Head
Protzer, Ulrike
)
Cell autonomous defense in the control of hepatitis B virus infection
(Project Head
Protzer, Ulrike
)
Imaging-unit
(Project Heads
Büning, Hildegard
;
Kashkar, Hamid
;
Latz, Eicke
;
Protzer, Ulrike
;
Schauss, Astrid
;
Utermöhlen, Olaf
)
Research Fellowships
Completed projects
Modulation of human endogenous retroviruses (HERVs) by CRISPR in human pluripotent stem cells
(Applicant
Vincendeau, Michelle
)
CRC/Transregios
Current projects
Decisive factors to induce cell death via oxeiptosis and the relationship to other forms of regulated cell death
(Project Head
Pichlmair, Andreas
)
Effects of constitutive cytokine signalling on tissue homeostasis and liver cell-intrinsic responsiveness to hepatitis virus infection
(Project Heads
Beisel, Claudia
;
Binder, Marco
;
Pichlmair, Andreas
)
Establishment and Fate of HBV cccDNA
(Project Heads
Protzer, Ulrike
;
Wettengel, Jochen
)
Functional analysis of molecular perturbations induced by Hepatitis B and D virus infection
(Project Head
Pichlmair, Andreas
)
Functions and degradation of endogenously generated viral RNA
(Project Head
Pichlmair, Andreas
)
Overcoming barriers for T cell therapy of hepatitis B and hepatocellular carcinoma
(Project Head
Protzer, Ulrike
)
Reconstitution of antiviral immunity and elimination of persisting hepatitis B virus infection
(Project Heads
Grimm, Dirk
;
Kosinska, Anna Dagmara
;
Protzer, Ulrike
)
The role of human endogenous retrovirus K as a modulator of microglial function in glioblastoma
(Project Heads
Lehnardt, Seija
;
Vincendeau, Michelle
)
The role of RIP kinase 1 in the decision of apoptosis and pyroptosis induction during intracellular bacterial infection
(Project Head
Ebert, Gregor
)
Completed projects
Redirection of T-cells against Hepatitis B virus infected cells: comparison of chimeric and recombinant T cell receptors
(Project Head
Protzer, Ulrike
)
T cell therapy with chimeric antigen receptors (CARs) recognizing hepatitis B surface antigen
(Project Head
Protzer, Ulrike
)
Major Research Instrumentation
Completed projects
Imaging MS part 3
LC-MS/MS for protein analytics part 1
LC-MS/MS for protein analytics part 2
Research Training Groups
Current projects
GRK 2668: Immune Master Switches in Allergies and Autoimmune Diseases
(Spokesperson
Biedermann, Tilo
)
Completed projects
GRK 300: Pathogenic Microorganisms: Molecular Mechanisms and Genomic Approaches
(Spokesperson
Clayton, Christine Elizabeth
)
