Freie Universität Berlin
Fachbereich Biologie, Chemie, Pharmazie
Institut für Biologie
Address
Königin-Luise-Straße 1-3
14195 Berlin
Deutschland
GERiT
This institution in GERiT
14195 Berlin
Projects
Research Units
Current projects
Autophagic regulation of synapse formation and maintenance
(Applicant
Hiesinger, Peter Robin
)
Comparative Quantitative Image Acquisition, Analysis and Modeling
(Applicants
Baum, Daniel
;
Hiesinger, Peter Robin
;
Von Kleist, Ph.D., Max
)
Coordination Funds
(Applicant
Hiesinger, Peter Robin
)
Decomposing virulence: host, pathogen, and microbiota contributions
(Applicant
Armitage, Sophie
)
FOR 2705: Dissection of a Brain Circuit: Structure, Plasticity and Behavioral Function of the Drosophila mushroom body
(Spokesperson
Fiala, André
)
FOR 5026: Integrating insect immunity, microbiota and pathogens
(Spokesperson
Rolff, Jens
)
FOR 5228: Membrane trafficking processes underlying presynaptic proteostasis
(Spokesperson
Kreutz, Michael R.
)
FOR 5289: From Imprecision to Robustness in Neural Circuit Assembly
(Spokesperson
Hiesinger, Peter Robin
)
From imprecise synapse seeding to robust synapse formation by stabilization mechanisms of early molecular scaffolds
(Applicants
Petzoldt, Astrid G.
;
Sigrist, Stephan J.
)
In vivo evolution of pathogen virulence; host immunity, microbiota, and pathogen interactions
(Applicant
Keshavarz, Ph.D., Maryam
)
Non-cell autonomous regulation of synaptic upscaling by neuronal autophagy
(Applicants
Maglione, Ph.D., Marta
;
Sigrist, Stephan J.
)
Presynaptic plasticity in the control of mushroom body memory formation
(Applicant
Sigrist, Stephan J.
)
Robust axonal branch patterning through stochastic filopodial dynamics
(Applicant
Hiesinger, Peter Robin
)
The evolution of symbiont, pathogen and immune system interactions in Blattodea
(Applicant
McMahon, Dino
)
Completed projects
Monoamine secretion and synaptic modulation during olfactory conditioning in Drosophila
(Applicant
Sigrist, Stephan J.
)
Project FAUNA: Influence of soil animals on organic matter transformation and structural properties of urban soil.
(Applicant
Weigmann, Gerd
)
Research Grants
Current projects
Autophagy-Enhancers to reduce sleep disturbances: a combined approach
(Applicants
Flöel, Agnes
;
Sigrist, Stephan J.
)
Enabling Identification and Impact of Synaptic Weight in Functional Networks
(Applicants
Brose, Nils
;
Fernandez Busnadiego, Ruben
;
Haucke, Ph.D., Volker
;
Helmstaedter, Moritz
;
Rizzoli, Ph.D., Silvio-Olivier
;
Rosenmund, Christian
;
Schuman, Erin M.
;
Sigrist, Stephan J.
)
Gene regulation of aggression and courtship
(Applicants
Küpper, Clemens
;
Nowick, Katja
)
Neuronal Interaction Dynamics During Neural Circuit Assembly - A live imaging and computational modeling approach for the Drosophila brain
(Applicants
Hiesinger, Peter Robin
;
Von Kleist, Ph.D., Max
)
Resistance versus tolerance: an evolutionary physiology approach
(Applicant
Armitage, Sophie
)
Completed projects
Active zone core proteins in interaction with synaptic Ca2+ channels
(Applicant
Sigrist, Stephan J.
)
A Drosophila Grip-Homologue in synaptic development and plasticity: an integrative study
(Applicant
Sigrist, Stephan J.
)
Genomic innovations underlying the evolution of termite sociality
(Applicants
Harrison, Mark C.
;
McMahon, Dino
)
Glutamate receptor field dynamics
(Applicant
Sigrist, Stephan J.
)
Mechanisms of host plant induced plasticity of cuticular hydrocarbon phenotypes in mustard leaf beetles
(Applicant
Geiselhardt, Sven
)
Molecular and Cellular Mechanisms of Neural Superposition in Drosophila
(Applicant
Hiesinger, Peter Robin
)
Molecular determinants of brain size and cognitive performance
(Applicant
Nowick, Katja
)
Nanoscale cellular and molecular fingerprints of synaptic diversity
(Applicant
Sigrist, Stephan J.
)
Single cell transcriptomics to investigate monoallelic expression as a potential trigger of Alzheimer’s disease
(Applicant
Nowick, Katja
)
Struktur-Funktions Analyse der aktiven Zone in Drosophila
(Applicant
Sigrist, Stephan J.
)
The molecular mechanisms of aminergic release at “en-passent” type II synaptic terminals of the fruit fly (Drosophila melanogaster).
(Applicant
Pflüger, Hans-Joachim
)
The role of hypusination-dependent translation for brain aging
(Applicant
Sigrist, Stephan J.
)
Untersuchungen zu Struktur, Funktion und phylogenetischer Verbreitung des Drosophila-Pipsquek-Proteins und seiner DNA-Bindungsdomäne
(Applicant
Lehmann, Michael
)
Priority Programmes
Current projects
Dynamics of chromosome evolution in termites: Inbreeding, novel chromosomal translocations and sociality
(Applicants
Huylmans, Ann Kathrin
;
McMahon, Dino
)
Recurring phenotypic loss: Repeatability of genome and regulatory evolution
(Applicants
Colgan, Ph.D., Thomas Joseph
;
Nowick, Katja
;
Stolle, Eckart
;
Wipfler, Benjamin
)
The significance of saprobic fungi for energy and matter turnover under varying substrate conditions - from individuals to soils
(Applicant
Camenzind, Tessa
)
Completed projects
Does topography matter? Predicting odor response maps and inhibitory interactions between glomeruli for the dorsal olfactory bulb.
(Applicants
Schmuker, Michael
;
Spors, Hartwig
)
Host Immune Strategies: Remembering, Resisting, Tolerating, and Being Specific
(Applicant
Armitage, Sophie
)
Identification and characterization of genes encoding proteins with polar expression in different Drosophila cells
(Applicant
Klämbt, Christian
)
Long Non-Coding RNAs in Primate Brain Evolution
(Applicants
Nowick, Katja
;
Stadler, Peter Florian
)
The evolutionary mechanisms optimizing neural circuit structure and function for skylight navigation across insect species
(Applicants
Nowick, Katja
;
Wernet, Mathias
)
The role of nicotinic acetylcholine receptors for the development of auditory brainstem circuits involved in temporal processing of sounds
(Applicant
Koch, Ursula
)
Emmy Noether Independent Junior Research Groups
Completed projects
Developmental evolution of sex-specific mechanisms underlying the Retinoblastoma pathway in the control of gametic cell fate and differentiation in plants
(Applicant
Johnston, Amal J.
)
Heisenberg Fellowships
Completed projects
Resistance versus tolerance: an evolutionary physiology approach
(Applicant
Armitage, Sophie
)
Heisenberg Grants
Completed projects
Resistance versus tolerance – an evolutionary physiology approach
(Applicant
Armitage, Sophie
)
WBP Position
Current projects
Cocktails and low concentrations; effects of antimicrobial peptide combinations on bacterial resistance
(Applicant
Murphy, Ph.D., Ronan
)
The way of the sprig: axo-dendritic morphogenesis in the Drosophila visual system
(Applicant
Wolterhoff, Neele
)
Collaborative Research Centres
Current projects
Homeostatic presynaptic plasticity in memory consolidation and sleep of the aging brain
(Project Head
Sigrist, Stephan J.
)
Lipid-mediated mitochondrial dysfunction in HFpEF during obesity
(Project Heads
Kintscher, Ulrich
;
Sigrist, Stephan J.
)
Completed projects
Active Zone Protein Transport and Autism
(Project Head
Sigrist, Stephan J.
)
Auditory processing deficits in autism: auditory brainstem disturbances and the role of neuroligin-3
(Project Head
Koch, Ursula
)
Bedeutung des Drosophila GRIP-Homologen für Entwicklung und Plastizität der neuromuskulären Synapse
(Project Head
Sigrist, Stephan J.
)
Central Tasks-SFB Headquarters and Administration
(Project Heads
Haucke, Ph.D., Volker
;
Sigrist, Stephan J.
)
"Closing the cycle": Sub-modules in synaptic vesicle membrane targeting, fusion and endocytosis
(Project Head
Sigrist, Stephan J.
)
Functional adjustment of neural circuits: Tonotopic gradients of timeprocessing auditory brainstem neurons
(Project Heads
Koch, Ursula
;
Leibold, Christian
)
Glutamate receptor trafficking in the integration of short- and long-term synaptic plasticity
(Project Heads
Herzel, Hanspeter
;
Sigrist, Stephan J.
)
In vivo analysis of active zone assembly
(Project Heads
Petzoldt, Astrid G.
;
Sigrist, Stephan J.
)
Mechanismen der Akkumulation von Ca2+-Kanälen an aktiven Zonen
(Project Head
Sigrist, Stephan J.
)
Organization of the synaptic active zone scaffold by Bruchpilot and RIM-binding protein
(Project Heads
Sigrist, Stephan J.
;
Wahl, Markus C.
)
Protein scaffolds in synaptic endomembrane degradation
(Project Head
Hiesinger, Peter Robin
)
SFB 958: Scaffolding of Membranes: Molecular Mechanisms and Cellular Functions
(Spokespersons
Haucke, Ph.D., Volker
;
Sigrist, Stephan J.
)
Synaptische Veränderungen und olfaktorisches Lernen von Drosophila melanogaster
(Project Head
Sigrist, Stephan J.
)
Research Fellowships
Completed projects
Der Einfluss multipler Prädatoren - phänotypische Integration von plastischem prädations-vermeidendem Verhalten, Morphologie und Lebensgeschichte
(Applicant
Mikolajewski, Dirk Johannes
)
Major Research Instrumentation
Completed projects
2-Photonen-Mikroskop
Konfokales Laserscanning Mikroskop
STED Konfokalmikroskop
Scientific Networks
Current projects
Comparative urban ecology: developing methods to assess urban social-ecological networks across realms and regions
(Applicant
Straka, Tanja
)
CRC/Transregios
Current projects
High resolution analysis of active zone cytomatrix remodeling
(Project Heads
Paulino, Cristina
;
Schultz, Carsten
;
Sigrist, Stephan J.
;
Walter, Alexander
)
Completed projects
Acute control of intracellular trafficking through Rab GTPases in living tissues in Drosophila
(Project Heads
Boutros, Michael
;
Hiesinger, Peter Robin
)
Research Training Groups
Completed projects
GRK 837: Functional Insect Science
(Spokesperson
Walz, Bernd
)
GRK 1123: Cellular Mechanisms of Learning and Memory Consolidation in the Hippocampal Formation
(Spokesperson
Schmitz, Dietmar
)
Major Instrumentation Initiatives
Completed projects
Lattice Light Sheet Microscope (LLSM)
Clusters of Excellence (ExStra)
Current projects
EXC 2049: NeuroCure
(Spokespersons
Dirnagl, Ulrich
;
Schmitz, Dietmar
)
