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Humboldt-Universität zu Berlin
Lebenswissenschaftliche Fakultät
Institut für Biologie

Address Invalidenstraße 110
10115 Berlin
Deutschland

GERiT This institution in GERiT

10115 Berlin

Projects

Research Grants
- Current projects
- Completed projects
Research Units
- Current projects
  - Epigenomic mapping of myogenic regulation in human muscle development
    (Applicant Ohler, Uwe )
  - FOR 2518: Functional dynamics of ion channels and transporters - DynIon -
    (Spokesperson Benndorf, Klaus )
  - FOR 5228: Membrane trafficking processes underlying presynaptic proteostasis
    (Spokesperson Kreutz, Michael R. )
  - FOR 5363: KI-FOR Fusing Deep Learning and Statistics towards Understanding Structured Biomedical Data
    (Spokesperson Greven, Sonja )
  - FOR 5705: NeuroFlame – Defence and demise of inflamed neurons
    (Spokesperson Friese, Manuel A. )
  - PRR7 as synaptic gatekeeper during neuroinflammation
    (Applicants Kreutz, Michael R. ; Mikhaylova, Marina )
  - Regularization strategies for interpretable deep models and robust explanations with application to genomics
    (Applicants Ohler, Uwe ; Samek, Wojciech )
  - Unveiling spatiotemporal dynamics and unconventional functions of the axonal autophagy–lysosomal system.
    (Applicant Mikhaylova, Marina )
- Completed projects
Independent Junior Research Groups
- Current projects
  - Monoaminergic neuromodulation of cortical circuits underlying economic investment decisions
    (Applicant Ott, Torben )
- Completed projects
  - Collective Information Processing - From Individual Sensory Inputs to Collective Motion and Decision Making
    (Applicant Romanczuk, Pawel )
  - The molecular mechanisms of clustered synaptic plasticity: focus on lysosomes
    (Applicant Mikhaylova, Marina )
Heisenberg Professorships
- Completed projects
  - Excitatory synapses: from structural biology to optical control
    (Applicant Plested, Andrew )
Heisenberg Grants
- Completed projects
  - Excitatory synapses: from structural biology to optical control
    (Applicant Plested, Andrew )
Reinhart Koselleck Projects
- Current projects
  - Large Brain Neuroscience in Elephants
    (Applicant Brecht, Michael )
Major Research Instrumentation
- Completed projects
Collaborative Research Centres
- Current projects
  - A comparative approach to the consolidation of kinship memory
    (Project Heads Brecht, Michael ; Mikhaylova, Marina )
  - A comparative cellular atlas of environmental plasticity in leaves
    (Project Heads Kaufmann, Kerstin ; Ohler, Uwe ; Wigge, Ph.D., Philip Anthony )
  - Role of mTORC1 and protein translation in memory consolidation in the neocortex
    (Project Heads Haucke, Ph.D., Volker ; Larkum, Matthew ; Mikhaylova, Marina )
  - Spectroscopic investigations of proton transfer processes and hydrogen bonded networks in channelrhodopsins and phytochromes
    (Project Head Bartl, Franz )
- Completed projects
  - Chromophore-protein interaction in the signaling state of rhodopsin
    (Project Heads Bartl, Franz ; Hofmann, Klaus Peter )
  - Experience-dependent development of the cortical representation of social touch
    (Project Head Brecht, Michael )
  - Regulation of organellar gene expression
    (Project Heads Börner, Thomas ; Weihe, Andreas )
  - Regulation of photosynthesis at the level of chloroplast transcription
    (Project Heads Börner, Thomas ; Liere, Karsten )
  - Synaptic conductances during sharp wave-ripple complexes
    (Project Heads Brecht, Michael ; Kempter, Richard ; Schmitz, Dietmar )
  - The role of microtubule detyrosination in dendritic structure and function
    (Project Head Mikhaylova, Marina )
Priority Programmes
- Current projects
  - Escaping the Salmonella-containing vacuole – Role of flagella-mediated damage, cytosolic motility, and host cell apoptosis in exit and transmission of Salmonella
    (Applicants Erhardt, Marc ; Hensel, Michael )
  - Molecular sensing mechanisms of phage infection mediated through the Zorya anti-bacteriophage defense system
    (Applicants Erhardt, Marc ; Popp, Philipp )
- Completed projects
CRC/Transregios
- Current projects
  - Central scientific project Z1 - Quantitative biology experiments and novel approaches for identifying integrators
    (Project Heads Kleine, Tatjana ; Klipp, Edda ; Kunz, Hans-Henning ; Leister, Dario ; Neuhaus, Ekkehard ; Ohler, Uwe ; Schmitz-Linneweber, Christian ; Schroda, Michael ; Treves, Ph.D., Haim )
- Completed projects
Research Fellowships
- Completed projects
  - Orbitofrontal cortical circuitry mediating post-decision confidence reports
    (Applicant Ott, Torben )
  - Regulation of long distance neuropeptide signaling in aging
    (Applicant Subkhangulova, Ph.D., Aygul )
Major Instrumentation Initiatives
- Completed projects
  - A modular dual 2-photon microscope for multimodal optogenetics, synapse biophysics and beyond
  - Analysis of highly dynamic subcellular mechanisms by Lattice Light Sheet Microscopy
Research Training Groups
- Completed projects
  - GRK 1123: Cellular Mechanisms of Learning and Memory Consolidation in the Hippocampal Formation
    (Spokesperson Schmitz, Dietmar )
  - GRK 1589: Sensory Computation in Neural Systems
    (Spokesperson Obermayer, Klaus )
  - GRK 1772: Computational Systems Biology
    (Spokesperson Klipp, Edda )
International Research Training Groups
- Completed projects
  - GRK 2403: Dissecting and Reengineering the Regulatory Genome
    (Spokesperson Ohler, Uwe )
Clusters of Excellence
- Completed projects
  - EXC 257: NeuroCure - Towards a Better Outcome of Neurological Disorders
    (Spokesperson Schmitz, Dietmar )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2002: Science of Intelligence (SCIoI)
    (Spokesperson Brock, Oliver )
  - EXC 2008: UniSysCat
    (Spokespersons Dobbek, Holger ; Drieß, Matthias ; Mroginski, Ph.D., Maria Andrea ; Rappsilber, Juri ; Thomas, Arne )
  - EXC 2025: Matters of Activity. Image Space Material
    (Spokespersons Mareis, Claudia ; Schäffner, Wolfgang )
  - EXC 2049: NeuroCure
    (Spokespersons Dirnagl, Ulrich ; Schmitz, Dietmar )
Graduate Schools
- Completed projects
  - GSC 86: Berlin School of Mind and Brain
    (Spokespersons Pauen, Michael ; Villringer, Arno )
NFDI technical and methodological consortia
- Current projects
  - GHGA – German Human Genome-Phenome Archive
    (Spokesperson Stegle, Ph.D., Oliver )

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