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Institution
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V.
Hans-Knöll-Institut (HKI)
Abteilung Molekulare und Angewandte Mikrobiologie
Address
Adolf-Reichwein-Straße 23
07745 Jena
Deutschland
GERiT
This institution in GERiT
07745 Jena
Projects
Research Grants
Current projects
Discovery of novel ribosomally synthesized and post-translationally modified peptides (RiPPs) originating from unusual two-domain precursors
(Applicant
Lackner, Gerald
)
Completed projects
AfuInf - Proteome and polysaccharidome of Aspergillus fumigatus at early stage of infection
(Applicant
Brakhage, Axel
)
Antimicrobial Effect of Nano-Rough Titanium Surfaces: Reduction of Microbial Adhesion and Mechanisms of Reduction
(Applicants
Brakhage, Axel
;
Jandt, Klaus D.
)
Biochemische Charakterisierung der Glycosyltransferase WbpL von Pseudomonas aeruginosa als potentielles Target für neue Antiinfektiva
(Applicant
Ramm, Michael
)
Biosynthese von GPD-D-Rhamnose bei Pseudomonas aeruginosa - Suche nach Targets für neuartige Antiinfektiva
(Applicant
Ramm, Michael
)
Future directions in cofactor research: Discovery and development of coenzyme F420-dependent bioprocesses
(Applicant
Lackner, Gerald
)
Melaninbiosynthesegene als Virulenzdeterminanten und cAMP-abhängige Signaltransduktion in dem opportunistisch human-pathogenen Pilz ASPERGILLUS FUMIGATUS
(Applicant
Brakhage, Axel
)
Molekulare Regulation der Penicillinbiosynthese in Aspergillus nidulans: Transkriptionsfaktoren, Transkriptionskomplexe und deren Kommunikation
(Applicant
Brakhage, Axel
)
Novel molecular mechanisms of iron sensing and homeostasis in filamentous fungi
(Applicants
Brakhage, Axel
;
Groll, Michael
;
Hortschansky, Peter
)
Priority Programmes
Completed projects
Evolution und Funktion von cis-/trans-Elementen pilzlicher Sekundärmetabolismusgene am Beispiel der Penicillinbiosynthese in Aspergillus nidulans
(Applicant
Brakhage, Axel
)
Holistic approach to genomics of human-pathogenic fungi: Data warehouse for integration of data on transcriptome, proteome and metabolome of Candida albicans and Aspergillus fumigatus
(Applicants
Brakhage, Axel
;
Hauser, Nicole
)
Identification of virulence determinants of the human-pathogenic fungus Aspergillus fumigatus by proteome analysis
(Applicant
Brakhage, Axel
)
Koordination des Schwerpunktprogrammes "Kolonisation und Infektion durch humanpathogene Pilze"
(Applicant
Brakhage, Axel
)
SPP 1160: Colonisation and Infection by Human-pathogenic Fungi
(Spokesperson
Brakhage, Axel
)
Research Units
Completed projects
Redox regulation, development and hyphal growth in Aspergillus nidulans
(Applicant
Brakhage, Axel
)
WBP Position
Current projects
Elucidation of the role of non-ribosomal peptides and of a statin produced by the nematode-trapping fungus, Duddingtonia flagrans, during the interaction with Caenorhabditis elegans
(Applicant
Stroe, Maria Cristina
)
Collaborative Research Centres
Current projects
Bacteria-triggered Activation of Fungal Silent Gene Clusters and Impact of Produced Compounds on Microorganisms
(Project Heads
Brakhage, Axel
;
Heinzel, Thorsten
)
Macromolecular prodrug nanoparticles for antimicrobial therapy
(Project Heads
Brakhage, Axel
;
Guerrero Sanchez, Ph.D., Carlos Antioco
)
Completed projects
Molekulare Mechanismen der Protektion und deren Regulation des lungen-pathogenen Pilzes Aspergillus fumigatus gegen Immuneffektorzellen
(Project Head
Brakhage, Axel
)
Molekulare Regulation der Penicillinbiosynthese in Aspergillus nidulans
(Project Head
Brakhage, Axel
)
CRC/Transregios
Current projects
Central Tasks of the Collaborative Research Centre
(Project Head
Brakhage, Axel
)
Cross-talk of Aspergillus fumigatus with neutrophilic granulocytes
(Project Heads
Brakhage, Axel
;
von Lilienfeld-Toal, Marie
)
Surface proteins of Lichtheimia corymbifera as virulence determinants
(Project Heads
Brakhage, Axel
;
Voigt, Ph.D., Kerstin
)
TRR 124: Pathogenic Fungi and their Human Host: Networks of Interaction - FungiNet
(Spokesperson
Brakhage, Axel
)
WBP Fellowship
Completed projects
Development of a virus biosensor platform based on multivalent synthetic nanoswitches
(Applicant
Gräwe, Alexander
)
Research Training Groups
Completed projects
GRK 745: Mucosal Host-Pathogen Interactions
(Spokesperson
Valentin-Weigand, Peter
)
Graduate Schools
Completed projects
GSC 214: Jena School for Microbial Communication (JSMC)
(Spokesperson
Brakhage, Axel
)
Clusters of Excellence (ExStra)
Current projects
EXC 2051: Balance of the Microverse
(Spokespersons
Brakhage, Axel
;
Küsel, Kirsten
)
Additional Information
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