Medizinische Hochschule Hannover
Institut für Molekulare und Translationale Therapiestrategien
Address
Carl-Neuberg-Straße 1
30625 Hannover
Deutschland
GERiT
This institution in GERiT
30625 Hannover
Projects
Research Grants
Current projects
Deciphering the role of miRNAs in Fabry disease pathology and therapy
(Applicant
Hoepfner, Jeannine
)
Functional requirement of telomere length and telomerase in the regulation of mitochondrial reactive oxygen species in cardiomyocyte health and disease
(Applicants
Bär, Ph.D., Christian
;
Chatterjee, Ph.D., Shambhabi
)
Targeting telomere dysfunction-related immune- and organ senescence in pulmonary and cardiovascular disease
(Applicants
Brandenberger, Ph.D., Christina
;
Bär, Ph.D., Christian
)
The molecular role of selected circRNAs in cardiac macrophage dynamics and inflammatory response during cardiac remodeling after myocardial infarction
(Applicant
Jung, Ph.D., Mira
)
Completed projects
Bedeutung Osteopontin-induzierter micro-RNAs auf die Progression der kardialen Fibrose
(Applicant
Lorenzen, Johan Matthes
)
Bedeutung von microRNAs für die Funktion endothelialer Progenitorzellen - Einfluss von asymmetrischem Dimethylarginin
(Applicant
Thum, Ph.D., Thomas
)
CARDINAL - Cardiomyocyte-derived vesicular non coding RNAs and post-ischemic cardiac remodeling
(Applicant
Thum, Ph.D., Thomas
)
MicroRNA-abhängige Zell-Zell-Kommunikation zwischen kardialen Fibroblasten und Kardiomyozyten bei pathologischer Herzhypertrophie
(Applicant
Thum, Ph.D., Thomas
)
Noncoding RNA based strategies to treat doxorubicin induced cardiotoxicity
(Applicant
Gupta, Ph.D., Shashi Kumar
)
Regulation, Diagnostics and Therapy focusing on the mineralocorticoid receptor involved in cardiac remodelling
(Applicants
Bauersachs, Johann
;
Thum, Ph.D., Thomas
)
Role of miRNAs in diabetic chronic wound repair
(Applicant
Thum, Ph.D., Thomas
)
Role of the long intergenic non-coding (linc) RNA NRON in cardiac disease
(Applicants
Regalla, Ph.D., Kumarswamy
;
Thum, Ph.D., Thomas
)
Significance of differentially expressed microRNAs and their target proteins in the development of autoimmune myocarditis in mouse model and patients
(Applicants
Kaya, Ziya
;
Müller, Oliver J.
)
Research Units
Completed projects
Testing of unwanted side effects of noncoding RNA oligonucleotide therapeutics in small and large animal models
(Applicant
Thum, Ph.D., Thomas
)
Clinical Research Units
Completed projects
Impact of the long non-coding RNA meg3 on unloading and repair during cardiac remodeling
(Applicants
Cebotari, Serghei
;
Thum, Ph.D., Thomas
)
KFO 311: Cardiac and pulmonary failure: mechanical unloading andrepair
(Spokesperson
Bauersachs, Johann
)
CRC/Transregios
Current projects
Circular RNAs as targets to prevent cardiac damage and to induce cardiomyocyte proliferation
(Project Heads
Bär, Ph.D., Christian
;
Thum, Ph.D., Thomas
)
Collaborative Research Centres
Current projects
Mechanisms, therapeutics and diagnostic potential of circular RNAs in HFpEF
(Project Head
Thum, Ph.D., Thomas
)
Completed projects
Der Methionin/Threonin-11-Polymorphismus des Surfactantprotein D und MicroRNA-abhängige Effekte auf den Verlauf von Asthma und Pneumonie
(Project Heads
Ochs, Matthias
;
Thum, Ph.D., Thomas
)
Clusters of Excellence
Completed projects
EXC 62: From Regenerative Biology to Reconstructive Therapy (REBIRTH)
(Spokespersons
Haverich, Axel
;
Thum, Ph.D., Thomas
)
Graduate Schools
Completed projects
GSC 108: Hannover Biomedical Research School (HBRS)
(Spokesperson
Schmidt, Reinhold Ernst
)
