Friedrich-Alexander-Universität Erlangen-Nürnberg
Naturwissenschaftliche Fakultät
Department Biologie
Address
Staudtstraße 5
91058 Erlangen
Deutschland
GERiT
This institution in GERiT
91058 Erlangen
Projects
Research Grants
Current projects
Functional characterization of the Arabidopsis dynamin-related GTPases AtGBPL1 & 3
(Applicant
Kost, Benedikt
)
Heterotrophic Nutrition Strategies of the Parasitic Plant Cuscuta
(Applicants
Albert, Markus
;
Stadler, Ruth
)
Mechanistic diversification within the microbial NLP cytolysin family
(Applicants
Albert, Isabell
;
Nürnberger, Thorsten
)
Molecular functions of class II Glycine-rich proteins (GRPs) in plant parasitism and plant immunity
(Applicant
Albert, Markus
)
Completed projects
Analyse des telotrophen Ovars von Tribolium durch Enhancertrap- und RNAi-Screens
(Applicant
Klingler, Martin
)
Analysis of a putative PSI receptor domain in plant inositol transporters
(Applicant
Sauer, Norbert
)
Analysis of the physiological role of Yang-cycle enzymes
(Applicant
Sauer, Norbert
)
Analysis of the role of the B cell inhibitory receptor Siglec-G in autoimmunity and infection models
(Applicant
Nitschke, Lars
)
Biodiversität extrem säuretoleranter eukaryontischer Mikroorganismen in ausgewählten Tagebaurestseen in Deutschland unter besonderer Berücksichtigung der Mikroalgenflora
(Applicant
Huss, Volker
)
Characterization of two putative polyol transporter gene families from Arabidopsis thaliana
(Applicant
Sauer, Norbert
)
Charakterisierung des Vhr1p-regulierten Biotin-Sensing in Bäckerhefe
(Applicant
Sauer, Norbert
)
Charakterisierung von Plasmodesmata und Klonierung von Plasmodesmatagenen unter Verwendung GFP-exprimierender Pflanzen
(Applicant
Sauer, Norbert
)
Compartments and Mechanisms of Plant Endocytosis
(Applicant
Kost, Benedikt
)
Control of polar plant cell growth: functional characterization of regulators and effectors of the tobacco pollen tube Rac/Rop GTPase Nit-Rac5
(Applicant
Kost, Benedikt
)
Defence-triggering molecules of the parasitic plant Cuscuta and the recognition by cell surface receptors
(Applicant
Albert, Markus
)
Die Rolle des Adaptorproteins Grb2 für die Reifung und Aktivierung von B- und T-Lymphozyten
(Applicant
Nitschke, Lars
)
Die Rolle maternaler Gene bei Oogenese und Frühentwicklung von Tribolium
(Applicant
Schoppmeier, Michael
)
Die Rolle pflanzlicher Zuckertransporter bei der Interaktion mit Nematoden
(Applicant
Sauer, Norbert
)
Entwicklung von spezifischen Markern zum Nachweis von Trematodenlarven im Gewässer und im Zwischenwirt mit Hilfe der PCR.
(Applicant
Haberl, Bernhard
)
Etablierung und Funktionen maternaler Proteingradienten im Tribolium-Blastoderm
(Applicant
Schoppmeier, Michael
)
Evolution of mRNA localization and the role of localized determinants in posterior patterning and growth zone determination of two short germ insects
(Applicant
Schoppmeier, Michael
)
Examining the function of Piccolino at the photoreceptor ribbon synapse
(Applicant
Brandstätter, Johann Helmut
)
Functional analysis of genes controlling protein trafficking through plasmodesmata using Arabidopsis thaliana T-DNA insertion mutants
(Applicant
Weingartner, Magdalena
)
Functional and physiological characterization of the Arabidopsis monosaccharide-transporter-like proteins At1g05030, At1g67300 and At1g79820 from endomembranes
(Applicant
Sauer, Norbert
)
Functional characterization of AtRUG8, a protein that modulates plasmodesmal movement of macromolecules, and of three 3 closely related proteins
(Applicant
Sauer, Norbert
)
Funktionelle Charakterisierung von Phloemproteinen aus Arabidopsis thaliana
(Applicant
Sauer, Norbert
)
Identifizierung und Charakterisierung von Vitamintransportern in Saccharomyces cerevisiae und Arabidopsis
(Applicant
Sauer, Norbert
)
Integrated computational and experimental study of embryonic patterning by sequential and oscillatory gene regulatory mechanisms
(Applicant
Klingler, Martin
)
Mechanisms of habitat selection of parasites in the host
(Applicant
Haas, Wilfried
)
Mechanisms regulating the maintenance of a mature skeletal musculature
(Applicant
Nguyen, Hanh T.
)
"Molecular characterization of a novel host cell binding and invasion factor by the major foodborne pathogen Campylobacter jejuni"
(Applicants
Böhm, Manja
;
Heimesaat, Markus M.
)
Molecular control of division site establishment in plants
(Applicant
Müller, Sabine
)
Molekulare Zusammensetzung, Entwicklung und Funktion der Photorezeptor-Bandsynapse der Säuger-Retina
(Applicant
Brandstätter, Johann Helmut
)
Musterbildung in der Wachstumszone des Kurzkeim-Embryos von Tribolium: "segmentation clock" oder Gapgen-Mechanismus?
(Applicant
Klingler, Martin
)
Musterbildungsprozesse im Follikelepithel von Tribolium castaneum
(Applicant
Schoppmeier, Michael
)
Parasitic molecular cues during plant-plant interaction - recognition and influence on host plants
(Applicant
Albert, Markus
)
Physiological and functional analysis of a family of tetracycline transporter-like proteins in Arabidopsis
(Applicant
Sauer, Norbert
)
Recruitment and phospho-regulation of key division site proteins in plants
(Applicant
Müller, Sabine
)
Regulation of differentiation in myeloid cells and B-cells by the adhesion recepters of the siglec family
(Applicant
Nitschke, Lars
)
Regulation of ROP signaling in cell division and cell expansion by a small ROPGAP family
(Applicant
Müller, Sabine
)
RUL1 to RUL3:Characterization of three novel genes from Arabidopsis thaliana
(Applicant
Sauer, Norbert
)
Semi-field studies on the importance of host-finding for the transmission of miracidia and cercariae
(Applicant
Haas, Wilfried
)
Transmission der Myxozoa durch Actinosporen: Wirtserkennung und Wirtsspezifität
(Applicant
Haas, Wilfried
)
Wirtsfindung der humanpathogenen Hakenwürmer
(Applicant
Haas, Wilfried
)
Wirtsfindung der humanpathogenen Hakenwürmer
(Applicant
Haas, Wilfried
)
Yeast mutants with drastically reduced fatty acid synthase activity: molecular background and consequences on cellular protein palmitoylation
(Applicant
Schweizer, Eckhart
)
Priority Programmes
Completed projects
Chemismus der Wirtsspezifität bei der Wirtserkennung von Parasiten
(Applicant
Haas, Wilfried
)
Proximo-distale Musterbildung bei Tribolium castaneum
(Applicant
Klingler, Martin
)
SPP 1108: Dynamics and Regulation of Plant Membrane Transport during the Formation of Cell-Specific and Organ-Specific Features
(Spokesperson
Sauer, Norbert
)
Zell/Zell-Sortierung von Membranproteinen des Siebelement/Geleitzellen-Komplexes und Analyse einer vermuteten Regulationsdomäne von AtSUC3
(Applicant
Sauer, Norbert
)
Zentrale Aufgaben des SPP 1108: Nutzung von Microarrays zur Analyse gemeinsam regulierter Transporter-Gene und zur Charakterisierung entsprechender Mutanten
(Applicant
Sauer, Norbert
)
Research Units
Current projects
CD22 and its regulation of BCR signaling strength in germinal center B cell fate and metabolism
(Applicant
Nitschke, Lars
)
Deciphering the Function and Regulation of the B Cell Intrinsic a2,6-Sialylation Network
(Applicants
Nimmerjahn, Falk
;
Werner, Anja
)
FOR 2886: PANDORA - Pathways triggering AutoimmuNity and Defining Onset of early Rheumatoid Arthritis
(Spokesperson
Krönke, Gerhard
)
FOR 2953: Sialic Acid as Regulator in Development and Immunity
(Spokesperson
Mühlenhoff, Martina
)
FOR 5560: Crosstalk between B cell metabolism and signaling
(Spokesperson
Jellusova, Julia
)
The importance of sialoglycans for lymphocyte development and function
(Applicant
Nitschke, Lars
)
Completed projects
Carbon acquisition during pathogenic development of Ustilago maydis and Colletotrichum graminicola
(Applicants
Kämper, Jörg
;
Sauer, Norbert
)
Deciphering the stage specific impact of cellular and humoral components modulating the onset of RA
(Applicants
Lux, Anja
;
Nimmerjahn, Falk
)
FOR 1234: iBeetle: Functional Genomics of Insect Embryogenesis and Metamorphosis
(Spokesperson
Bucher, Gregor
)
Identification of short-germ-specific segmentation genes in Tribolium: We want to identify and functionally analyze novel genes that genes that are required for sequential segmentation in a cellularized environment, as well as genes involved in the setup of the Tribolium antrior-posterior axis
(Applicant
Klingler, Martin
)
Molecular and physiological characterization of vacuolar disaccharide and polyol transporters and of vacuolar monosaccharide transporter-like proteins
(Applicant
Sauer, Norbert
)
Procedure for a high throughput RNAi screen for the second phase of the iBeetle screen
(Applicants
Bucher, Gregor
;
Klingler, Martin
)
Redirection of photoassimilate partitioning by biotrophic, hemibiotrophic and mutualistic fungi through altered transporter gene expression
(Applicant
Sauer, Norbert
)
The follicle stem cell lineage in telotrophic Tribolium oogenesis
(Applicant
Schoppmeier, Michael
)
Untersuchungen zur Rolle von CD22 und Siglec-G in der Regulation von B-Zell-Aktivierung und systemischer Autoimmunität
(Applicant
Nitschke, Lars
)
Emmy Noether Independent Junior Research Groups
Completed projects
Patterning of cortical contractility during cytokinesis
(Applicant
Zanin, Esther
)
Heisenberg Fellowships
Completed projects
Molecular encounters at the plant division site
(Applicant
Müller, Sabine
)
Heisenberg Grants
Completed projects
Molecular encounters at the plant cell division site
(Applicant
Müller, Sabine
)
Collaborative Research Centres
Current projects
Kinase cascades in neutrophils as therapeutic target in pemphigoid diseases
(Project Heads
Bieber, Katja
;
Lux, Anja
)
Mechanics of molecular machines involved in plant cytokinesis
(Project Heads
Müller, Sabine
;
Schäffer, Erik
)
Completed projects
Autoregulation der Fettsäuresynthase-Biosynthese in Hefe
(Project Head
Schweizer, Eckhart
)
Die transkriptionelle Steuerung des Autotrophie/Heterotrophie-Übergangs bei Chlorella kessleri
(Project Heads
Klebl, Franz
;
Sauer, Norbert
)
Modulation of cellular processes and Rac/Rop (Rho) activity in Arabidopsis by Pto TTSS effector proteins
(Project Head
Kost, Benedikt
)
Neu-entwickelte Sialinsäurederivate zur Verstärkung der B-Zellaktivierung über CD22 und deren möglicher therapeutischer Einsatz
(Project Head
Nitschke, Lars
)
Regulation der blütenspezifischen Expression von AtSUC1 durch bZIP
(Project Head
Sauer, Norbert
)
Regulation des Sink/Source-Überganges während der Blattentwicklung
(Project Head
Sauer, Norbert
)
Regulation des Sink/Source-Überganges während der Blattentwicklung von Arabidopsis thaliana
(Project Head
Sauer, Norbert
)
Regulation von Differenfzierungsentscheidungen in der myeloiden und B-Zell-Linie durch Adhäsionsrezeptoren der Siblec-Familie
(Project Head
Nitschke, Lars
)
Signaltransduktion und Genaktivierung Inositol/Cholin-regulierter Sturkturgene in der Hefe Saccharomyces cerevisiae
(Project Heads
Schweizer, Eckhart
;
Schüller, Hans-Joachim
)
Targeting of CD22 on B cell lymphoma cells and on B cells in autoimmune diseases
(Project Head
Nitschke, Lars
)
The role of Siglecs and sialic acids in the resolution of inflammation
(Project Heads
Nitschke, Lars
;
Steffen, Ulrike
)
Untersuchungen zur Rolle von CD22 und Siglecs in der B-Zell-Differenzierung und B-Zell-Signalleitung mit Hilfe genetisch-veränderter Mäuse
(Project Head
Nitschke, Lars
)
Research Fellowships
Completed projects
Control of Rho family GTPases during cytokinesis
(Applicant
Zanin, Esther
)
Role of the E-proteins E2A and E2-2 in the control of B cell immunity
(Applicant
Wöhner, Miriam
)
Major Research Instrumentation
Completed projects
Konfokalmikroskop
Konfokal/Multiphoton/FCS Mikroskop
Plant growth chamber facility
CRC/Transregios
Completed projects
Central Tasks
(Project Head
Nitschke, Lars
)
Deciphering the Regulation of the B Cell intrinsic Glycoslyation Network
(Project Heads
Lux, Anja
;
Nimmerjahn, Falk
)
The role of Siglec proteins in B cell activation and autoimmunity
(Project Head
Nitschke, Lars
)
Transgenic mouse unit
(Project Heads
Nitschke, Lars
;
Winkler, Thomas
)
TRR 130: B Cells: Immunity and Autoimmunity
(Spokesperson
Nitschke, Lars
)
Research Training Groups
Current projects
GRK 2504: Novel antiviral approaches: from small molecules to immune intervention
(Spokesperson
Überla, Klaus
)
GRK 2599: FAIR - Fine-Tuners of the Adaptive Immune Response
(Spokespersons
Jäck, Hans-Martin
;
Zaiss, Mario M.
)
Completed projects
GRK 592: Lymphocytes: Differentiation, Activation and Deviation
(Spokesperson
Jäck, Hans-Martin
)
GRK 805: Protein-Protein Interactions in Signal Transduction
(Spokesperson
Hillen, Wolfgang
)
GRK 1660: Key Signals of Adaptive Immune Response
(Spokesperson
Jäck, Hans-Martin
)
GRK 1962: Dynamic Interactions at Biological Membranes - From Single Molecules to Tissue
(Spokesperson
Böckmann, Rainer
)
