Universitätsklinikum Düsseldorf
Institut für Medizinische Mikrobiologie und Krankenhaushygiene
Address
Universitätsstraße 1
40225 Düsseldorf
Deutschland
GERiT
This institution in GERiT
40225 Düsseldorf
Projects
Research Grants
Current projects
Impact of communication of plasmacytoid dendritic cells and dendritic cell progenitors in the bone marrow during sepsis-induced immune dysregulation
(Applicants
Flohé, Stefanie
;
Scheu, Stefanie
)
Completed projects
Antigenvariabilität des Adhäsins P50 von Mycoplasma hominis: Molekulare Ursachen und deren Auswirkungen auf die Virulenz des Keims
(Applicant
Hadding, Ulrich
)
Characterization of BATF functions in plasmacytoid dendritic cell development and type I interferon production in antiviral immune responses
(Applicant
Scheu, Stefanie
)
Die neu identifizierte Serinprotease PrtA von Streptococcus pneumoniae: Ein Zellwand-assoziierter Virulenzfaktor?
(Applicant
Zysk, Gregor
)
Funktionen des TNF-Rezeptors p55 und des Lymphotoxin Beta Rezeptors in vivo
(Applicant
Pfeffer, Klaus
)
Generation and characterization of a TRAP1 knockout mouse
(Applicant
Würthner, Jens
)
High-throughput genotyping of complex loci in humans and microbes
(Applicant
Dilthey, Alexander
)
Molecular functions of the murine guanylate binding protein (mGBP) 2 in the immune defense against Toxoplasma gondii
(Applicant
Pfeffer, Klaus
)
Oberflächenlokalisierte Hitzeschockproteine in Mycoplasma hominis: Interaktion des Membranproteins P60 mit dem HSP70-homologen P80
(Applicant
Henrich, Birgit
)
Priority Programmes
Completed projects
Charakterisierung von antimikrobiellen Effektormechanismen in humanen Endothelzellen nach Stimulation mit Interferon
(Applicant
Däubener, Walter
)
The role of the Lymphotoxin beta receptor in innate immunity
(Applicant
Pfeffer, Klaus
)
Emmy Noether International Fellowships
Completed projects
Aufklärung der molekularen Grundlagen und biologischen Funktion von nicht-klassischen MHC Klasse Ib restringierten Effektor T Zellen
(Applicant
Scheu, Stefanie
)
Research Units
Completed projects
Antimicrobial effects mediated by the regulation of the local tryptophan concentration: diverse effects mediated by different tryptophan degrading enzymes in mice and men
(Applicant
Däubener, Walter
)
Central tasks of the Research Unit 729
(Applicant
Pfeffer, Klaus
)
FOR 729: Anti-infective Effector Programmes: Signals and Mediators
(Spokesperson
Pfeffer, Klaus
)
The biological role of interferon y induced 65 kDa GBPs as effector molecules in host defense
(Applicant
Pfeffer, Klaus
)
Visualization of IL-22 expressing cells during anti-infectious immune responses
(Applicant
Scheu, Stefanie
)
Emmy Noether Independent Junior Research Groups
Completed projects
Die zelluläre Initiation der Typ I Interferon Antwort in vivo
(Applicant
Scheu, Stefanie
)
Collaborative Research Centres
Completed projects
Activation and differentiation of macrophages mediated by proinflammatory cytokines
(Project Head
Pfeffer, Klaus
)
Analyse der Funktionen von Interferon y-induzierten Genen bei der angeborenen Infektionsabwehr
(Project Head
Pfeffer, Klaus
)
Aufklärung der Funktionen der Janus Kinase-2 (JAK2)
(Project Head
Pfeffer, Klaus
)
Dynamics and trafficking of mGBP protein complexes within membranous compartments
(Project Heads
Degrandi, Daniel
;
Pfeffer, Klaus
)
Effektormechanismen bei infektiösen Encephalitiden
(Project Heads
Däubener, Walter
;
Hadding, Ulrich
)
Generierung und Analyse eines Kinectin-defizienten Mausstammes
(Project Head
Pfeffer, Klaus
)
Generierung und Analyse von sodd-und tab2-defizienten Mausstämmen
(Project Heads
Endres, Robert
;
Pfeffer, Klaus
)
Herpesvirusinfektionen bei der Organtransplantation: Rolle des Cytomegalovirus bei der Pathogenese des chronischen Transplantatversagens
(Project Heads
Heidecke, Claus-Dieter
;
Koszinowski, Ulrich H.
;
Pfeffer, Klaus
)
Molecular Analysis of Lymphotoxin-ß-Receptor and Tumor Necrosis Factor Receptor p55 Mediated Hepatic Regeneration Processes
(Project Head
Pfeffer, Klaus
)
Regulation immunologischer Funktionen in Mikrogliazellen und Astrozyten
(Project Head
Fischer, Hans-Georg
)
The role of TNF recptor p55 (TNFRp55) for liver failure during acute sepsis and bacterial infections
(Project Heads
Beer-Hammer, Sandra
;
Pfeffer, Klaus
)
Research Training Groups
Current projects
GRK 2158: Natural products and natural product analogs against therapy-resistant tumors and microorganisms: new lead structures and modes of action
(Spokesperson
Gohlke, Holger
)
Completed projects
GRK 320: Pathological Processes of the Nervous System: From Gene to Behavior
(Spokesperson
Reifenberger, Ph.D., Guido
)
GRK 1045: Modulation of Host Cell Functions to Treat Viral and Bacterial Infections
(Spokesperson
Dittmer, Ulf
)
GRK 1949: Immune Response in Infectious Diseases - Regulation between Innate and Adaptive Immunity
(Spokesperson
Westendorf, Astrid M.
)
