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Universitätsklinikum Aachen, AöR
Institut für Biochemie und Molekularbiologie

Address Pauwelsstraße 30
52074 Aachen
Deutschland

GERiT This institution in GERiT

52074 Aachen

Projects

Priority Programmes
- Completed projects
  - Cell cycle control by the Myc/Max/Mad network: Regulation of Mad by cyclin E/CDK2 and identification and characterization of Mad1 target genes Zellzyklusregulation durch das Myc/Max/Mad Netzwerk: Regulation von Mad durch Cyclin E/CDK2 und Identifizierung und Charakterisierung von Mad Zielgenen
    (Applicant Lüscher, Bernhard )
Research Grants
- Current projects
  - Identification and characterisation of enzymes that control mono(ADP-ribosyl)ation in mitochondria
    (Applicant Feijs, Ph.D., Karla )
  - The role of ADP-Ribose as mRNA cap during cellular starvation
    (Applicant Zaja, Roko )
- Completed projects
Collaborative Research Centres
- Completed projects
  - Central Services of the Collaborative Research Program
    (Project Heads Floege, Jürgen ; Müller-Newen, Gerhard )
  - Cytokine-dependent regulation of the MAD1 promoter and the MAD1 protein
    (Project Head Lüscher, Bernhard )
  - Dynamics and topology of the Jak/STAT signalling pathway
    (Project Head Müller-Newen, Gerhard )
  - Fused soluble receptors as highly potent cytokine inhibitors
    (Project Head Müller-Newen, Gerhard )
  - Konfokale Laser-scanning Mikroskopie
    (Project Head Müller-Newen, Gerhard )
  - Regulation des potentiellen Tumorsuppressorgens mad 1 durch Zytokine
    (Project Head Lüscher, Bernhard )
  - Regulation of IL-31 in pathogenesis and therapy of T-cell mediated allergic immediate type reactions and inflammatory skin diseases
    (Project Heads Baron, Jens Malte ; Lüscher, Bernhard )
  - Signaltransduktion der Interleukin-6-Typ Zytokin-vermittelten Migration von T-Zellen
    (Project Heads Heinrich, Peter C. ; Schaper, Fred )
  - Struktur-/Funktionsanalysen der Janus-Kinasen und deren Bedeutung für die Signaltransduktion von Zytokinen der IL-6-Familie
    (Project Head Heinrich, Peter C. )
Clinical Research Units
- Current projects
  - KFO 344: Untangling and Targeting Mechanisms of Myelofibrosis in Myeloproliferative Neoplasms (MPN)
    (Spokesperson Brümmendorf, Tim Henrik )
  - Molecular targeting of STAT3-activating cytokines in the MPN pre-fibrotic niche
    (Applicants Müller-Newen, Gerhard ; Schemionek-Reinders, Mirle )
Major Instrumentation Initiatives
- Completed projects
  - Advanced Mass Spectrometry Imaging of Metals and Biomolecules in Brain and Liver
    (Applicant Amunts, Katrin )
Research Training Groups
- Completed projects
  - GRK 1035: Biointerface - Detection and Control of Interface-induced Biomolecular and Cellular Functions
    (Spokesperson Möller, Martin )

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